Protein Higher Order Structure


  • Characterize and detect subtle differences in protein higher order structure (HOS)
  • Compare protein conformers, environmental effects on structure, and fidelity of structure upon mutation or other evolutions
  • Characterize Temperature-Dependent Conformational Changes
  • Analyze Membrane Protein structure and conformational changes

Other Services

Protein Small Molecule Interaction

  • Gain detailed insights into - ligand-protein interactions.
  • Pinpoint amino acid level hotspots to locate binding interactions.
  • Generate a detailed map of ligand-induced higher-order structural changes.

Protein-Protein Interaction

  • Map the specific regions of interactions between proteins.
  • Characterize drug/receptor interactions, protein aggregation, or dimerization.

Protein Higher Order Structure

  • Characterize and detect subtle differences in protein higher order structure (HOS).
  • Use HOS for measuring comparability studies for characterizing biosimilar-innovator differences, expression platforms, formulation, or changes based on buffer or environmental conditions.

Case Studies

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Protein Higher Order Structure

Protein Higher Order Structure

  • Characterize and detect subtle differences in protein higher order structure (HOS)
  • Use HOS for measuring comparability studies for characterizing biosimilar-innovator differences, expression platforms, formulation, or changes based on buffer or environmental conditions
  • Characterize Temperature-Dependent Conformational Changes
  • Analyze Membrane Protein structure and conformational changes

Case Studies

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