Identify a therapeutic target by characterizing protein/protein interactions in a high throughput fashion.
Fast, high-resolution epitope. mapping. Provides conformational, in-solution epitope data.
Time-resolved studies of protein binding and conformational changes.
PLIMB: Plasma Induced Modification of Biomolecules
PLIMB is a novel and groundbreaking technology for performing hydroxyl radical protein footprinting–a structural mass spectrometry technique which provides structural data of a protein in its native solution and conformation.
PLIMB utilizes plasma to generate microsecond bursts of hydroxyl radicals, which modify and label solvent-accessible regions of a protein.